MOTS-c 10 mg Overview
MOTS-c is a mitochondria-encoded peptide that regulates metabolism, supports mitochondrial efficiency, and promotes cellular resilience. By activating AMPK and stress-response pathways, MOTS-c encourages improved energy utilization, metabolic balance, and overall performance while supporting healthy aging.
Peptide Profile
- Name: MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c)
- CAS Number: 1627580-64-6
- Molecular Formula: C101H152N28O22S2 (free peptide)
- Main Function: Metabolic regulator, exercise-mimetic, AMPK activator
- Mechanism: Enhances AMPK signaling, optimizes glucose uptake and fat oxidation, and coordinates stress-response and antioxidant gene expression
Key Benefits
- Supports insulin sensitivity and healthy glucose handling
- Boosts endurance, physical performance, and energy utilization
- Promotes mitochondrial efficiency and cellular stress resilience
- Encourages fat oxidation and favorable body composition
- Reduces oxidative stress and inflammation linked to aging
- Supports metabolic health and overall longevity pathways
- Potential synergistic effects with exercise and high-performance training
Research & Applications
- Identified as a mitokine that coordinates nuclear gene programs from mitochondria under metabolic stress
- Animal studies show improved endurance, insulin sensitivity, and metabolic flexibility
- Observational human data link MOTS-c levels with exercise performance and metabolic health
- Applications include performance enhancement, metabolic optimization, recovery support, and healthy-aging interventions
Possible Side Effects
- Generally well-tolerated in preclinical and anecdotal use
- Mild transient headache or nausea reported in rare cases
- Minor injection site redness or irritation possible
Note: Informational content only.